Factors associated with using opiates while under extended-release naltrexone blockade: A descriptive pilot study
نویسندگان
چکیده
منابع مشابه
Factors associated with willingness to take extended release naltrexone among injection drug users
BACKGROUND Although opioid-agonist therapy with methadone or buprenorphine/naloxone is currently the mainstay of medical treatment for opioid use disorder, these medications often are not well accepted or tolerated by patients. Recently, extended release naltrexone (XR-NTX), an opioid antagonist, has been advanced as an alternative treatment. The willingness of opioid-addicted patients to take ...
متن کاملThe Vivitrol pilot program (VPP): initial quantitative findings from an extended-release naltrexone study
Background In 2010, the FDA approved the use of extended-release injectable naltrexone (Vivitrol©) for the treatment of opioid dependence. Preliminary evidence from prior studies indicates that monthly injections of Vivitrol are effective in treating opioid dependence after initial detoxification. This longitudinal exploratory study measures demographics, medication adherence, sobriety (urinaly...
متن کاملTreating Opioid Dependence With Injectable Extended-Release Naltrexone (XR-NTX)
OBJECTIVES Once-monthly intramuscular extended-release naltrexone (XR-NTX) has demonstrated efficacy for the prevention of relapse in opioid dependence, providing an alternative to agonist or partial agonist maintenance (ie, methadone and buprenorphine). The question remains, for whom is this unique treatment most efficacious and can patient-treatment matching factors be identified? METHODS A...
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BACKGROUND Morphine sulfate and naltrexone hydrochloride extended-release capsules (EMBEDA, King Pharmaceuticals, Inc., Bristol, TN), indicated for management of chronic, moderate-to-severe pain, contain pellets of extended-release morphine sulfate with a sequestered naltrexone core (MS-sNT). Taken as directed, morphine provides analgesia while naltrexone remains sequestered; if tampered with b...
متن کاملLong-term opioid blockade and hedonic response: preliminary data from two open-label extension studies with extended-release naltrexone.
The emergence of extended-release naltrexone (XR-NTX) raises the opportunity to explore the role of endorphin blockade on hedonic response during long-term alcohol dependence treatment. A hedonic survey was administered to 74 alcohol dependent patients treated for an average of 3.5 years with nearly continuous month-long intramuscular XR-NTX. The paper-and-pencil, one-time survey asked patients...
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ژورنال
عنوان ژورنال: Journal of Substance Abuse Treatment
سال: 2018
ISSN: 0740-5472
DOI: 10.1016/j.jsat.2016.12.006